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Table 1 Baseline characteristics of the population

From: Renin Angiotensin system-modifying therapies are associated with improved pulmonary health

Variable

ACE-Is

ARBs

Control

Number of Subjects (%)

101,613 (47.2)

24,526 (11.4)

89,086 (41.4)

Sex (%)

 Female

47,195 (46.5)

12,550 (51.2)

52,189 (58.6)

Mean age (years ± SD)

62.91 (13.5)

62.05 (±13.3)

64.20 (±13.8)

Race (%)

 White

56,522 (55.6)

11,502 (46.9)

50,660 (56.9)

 Black

5032 (5.0)

1531 (6.2)

7359 (8.3)

 Others

2854 (2.8)

834 (3.4)

2432 (2.7)

 Unknown

37,195 (36.6)

10,659 (43.5)

28,635 (32.1)

Comorbidities (ICD-9 codes)

 Infectious (001–139)

14,183 (14.0)

3299 (13.5)

15,016 (16.9)

 Blood (280–289)

15,762 (15.5)

3858 (15.7)

18,105 (20.3)

 AMI (410)

3081 (3.0)

308 (1.3)

1503 (1.7)

 Angina pectoris (413)

4022 (4.0)

775 (3.2)

3594 (4.0)

 Cardiac dysrhythmias (427)

13,591 (13.4)

2805 (11.4)

15,769 (17.7)

 Heart failure (428)

4702 (4.6)

869 (3.5)

6859 (7.7)

 Respiratory (460–519)

33,081 (32.6)

7995 (32.6)

28,836 (32.4)

Other Treatments

 Statin (%)

43,298 (42.6)

9393 (38.3)

33,043 (37.1)

 Flu vaccine (%)

35,550 (35.0)

7914 (32.3)

32,498 (36.5)

 T2D (%)

5423 (5.3)

1218 (5.0)

5281 (5.9)

Other Information

 Mean follow up time (days)

1663.08

1603.33

1664.05

 STD (+/−)

593.43

611.68

599.37

  1. Medicare (a small % of the Humana dataset) does not report patient race and will be reported as unknown here. Incidence of comorbidities in the 12 month pre-index period for all study groups. *Respiratory does not include codes covered by infectious, inflammatory or structural outcomes