Responders at 24 weeks (HbA1c < 7% or ≥ 1% reduction) n = 1188 | Nonresponders at 24 Weeks (HbA1c ≥ 7% and < 1% reduction) n = 297 | P value | |
---|---|---|---|
Age, years | 57.8 (9.9) | 57.2 (10.1) | 0.323 |
Age group | 0.833 | ||
< 65 years | 893 (75.2) | 225 (75.8) | |
≥ 65 years | 295 (24.8) | 72 (24.2) | |
Gender | 0.012 | ||
Women | 543 (45.7) | 160 (53.9) | |
Men | 645 (54.3) | 137 (46.1) | |
Duration of T2DM, years | 10.3 (6.6) | 9.7 (6.5) | 0.159 |
Weight, kg | 87.5 (19.7) | 85.8 (21.6) | 0.201 |
BMI, kg/m2 | 31.3 (5.70) | 30.9 (5.70) | 0.213 |
HbA1c, % | 9.1 (1.2) | 8.3 (0.9) | < 0.001 |
HbA1c, mmol/mol | 99 (13) | 91 (10) | < 0.001 |
FBG, mg/dL | 186.7 (52.0) | 158.5 (42.2) | < 0.001 |
≥ 1 OAMs Targeting PPGa | 1111 (93.5) | 290 (97.6) | 0.006 |
SU, yes | 1067 (89.8) | 284 (95.6) | 0.002 |
2 OAMs | 790 (66.5) | 194 (65.3) | 0.701 |
MET/SU | 614 (51.7) | 167 (56.2) | – |
3 OAMs | 389 (32.7) | 100 (33.7) | 0.761 |
MET/SU/TZD | 346 (29.1) | 89 (30.0) | – |
4 OAMs | 7 (0.6) | 3 (1.0) | 0.429 |