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Table 1 Classes of anti-hyperglycemia medications

From: Better care for people with diabetes and endocrine diseases

Class of drug Year first approved in US
1. Insulin  
•Animal insulins 1923
•Human insulins 1982
•Insulin analogs 1996
2. Sulfonylureas 1955
3. Biguanide-Metformin 1995 (1957 in Europe)
4. Alpha glucosidase inhibitors 1995 (1990 in Germany)
5. Amylin analog 1995
6. Thiazolidinediones 1997
7. Glucagon-like peptide receptor agonists 2005
8. Dipeptidyl-peptidase inhibitors 2006
9. Bile acid sequestrant-Colesevelam 2008
10. Dopamine agonist-Bromocryptine 2009
11. Sodium-glucose co-transporter 2 inhibitors 2013