Fig. 3
From: Charcot stage 0: A review and consideratons for making the correct diagnosis early
Histology Slides demonstrating histologic changes seen in patient with Charcot Neuroarthropathy [36]. The figure on the left demonstrates a normal joint; here it is a distal interphalangeal joint. Note the smooth cartilage surface, organization of the chondrocytes in regular rows, and the subchondral cancellous bone is intact. The figure on the right demonstrates a joint afflicted by CN. Note the absence of cartilage and replacement with fibro-osseous tissue. The major histologic changes are evident at the joint, as demonstrated in the normal and pathologic samples above