• Donor: older age and high body mass index • Surgical procedure: extensive manipulation of the graft and long ischemic period • Recipient: higher body mass index and posttransplant weight gain; donor age, hepatitis C virus and donor-positive with recipient-negative CMV status • Type of pancreas transplantation: pancreas transplantation alone and pancreas after kidney transplantation • Immunosuppressive regimen: prolonged use of glucocorticoids and use of tacrolimus • Follow-up: number of acute rejection episodes, loss of the kidney graft in pancreas-kidney transplantation, and long duration of the transplant |  |