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Table 4 Factors related to bone and mineral metabolism disturbances following pancreas transplantation

From: Diabetes and other endocrine-metabolic abnormalities in the long-term follow-up of pancreas transplantation

• Preexisting: older age, female gender, long duration of pretransplant kidney failure, history of pretransplant fracture, severity of hyperparathyroidism secondary to kidney disease

• Inherent to transplant status: kidney function, use of immunosuppressive agents (especially glucocorticoids and calcineurin inhibitors)

• Other factors commonly observed after transplantation: hypogonadism, vitamin D deficiency, persistent parathyroid disease, thyroid abnormalities

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