Natural history of ROHHAD syndrome: development of severe insulin resistance and fatty liver disease over time

Table 1 Childhood labs

	Value	Reference Range
IGF-1, ng/mL	41	70–288
GH stimulation testing	GH undetectable at baseline and all-time points after stimulation with arginine and insulin-induced hypoglycemia to 49 mg/dL
Prolactin, ng/mL	50	1–17
ADH, pg/mL	1.7	< 1.7
Serum Na, meq/L	156	132–145
Morning cortisol, mcg/dL	12.7	< 20
TSH, mU/L	0.87	0.3–5.5
Free T4, ng/dL	0.99	0.73–1.79
Estradiol at age 12, pg/mL	8.0	< 10 prepubertal
FSH, mIU/L	0.2	3–26
LH, mIU/L	0.5	2–105

Abbreviations: IGF-1, insulin like growth factor-1; GH, growth hormone; TSH, thyroid stimulating hormone; LH, luteinizing hormone. A leptin level at age 22 was measured at 99 ng/ml and an adiponectin level was 3 mcg/ml which was low

ISSN: 2055-8260