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Table 2 Labs and Tumor Properties on Imaging and Histopathology

From: Acromegaly: a clinical perspective

Factor Total
(N = 136)
n n (%) or Median [P25, P75]
Random GH level at Dx 125 8.2[3.2,34.0]
IGF-1 level at Dx 134 769.0[567.0,956.0]
2-h nadir post OGTT GH at Dx 44 4.4[1.6,16.9]
Most recent random GH level 128 0.61[0.31,1.8]
Most recent IGF-1 level 134 205.5[155.0,281.0]
Most recent 2-h nadir post OGTT GH 32 0.32[0.19,0.90]
Months between GH measures 116 21.5[7.9,65.3]
Months between IGF-1 measures 131 34.7[12.8,87.9]
Tumor size 135  
 • Macroadenoma   111(82.2)
 • Microadenoma   24(17.8)
Tumor length/antero-posterior 126 16.0[11.0,22.0]
Tumor width/transverse 116 16.0[10.5,20.0]
Tumor height/craniocaudal 105 14.0[10.0,20.0]
GH staining 136 124(91.2)
GH staining type 65  
 • Rare   29(44.6)
 • Diffuse   36(55.4)
Pituitary hormone co-staining 136 89(65.4)
 • TSH 136 57(41.9)
 • Prolactin 136 57(41.9)
 • ACTH 136 12(8.8)
 • FSH 136 4(2.9)
Granulation pattern 23  
 • Densely   17(73.9)
 • Sparsely   6(26.1)
Cavernous sinus invasion 132 59(44.7)
Optic chiasm compression 132 43(32.6)