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Table 2 Labs and Tumor Properties on Imaging and Histopathology

From: Acromegaly: a clinical perspective

Factor

Total

(N = 136)

n

n (%) or Median [P25, P75]

Random GH level at Dx

125

8.2[3.2,34.0]

IGF-1 level at Dx

134

769.0[567.0,956.0]

2-h nadir post OGTT GH at Dx

44

4.4[1.6,16.9]

Most recent random GH level

128

0.61[0.31,1.8]

Most recent IGF-1 level

134

205.5[155.0,281.0]

Most recent 2-h nadir post OGTT GH

32

0.32[0.19,0.90]

Months between GH measures

116

21.5[7.9,65.3]

Months between IGF-1 measures

131

34.7[12.8,87.9]

Tumor size

135

 

 • Macroadenoma

 

111(82.2)

 • Microadenoma

 

24(17.8)

Tumor length/antero-posterior

126

16.0[11.0,22.0]

Tumor width/transverse

116

16.0[10.5,20.0]

Tumor height/craniocaudal

105

14.0[10.0,20.0]

GH staining

136

124(91.2)

GH staining type

65

 

 • Rare

 

29(44.6)

 • Diffuse

 

36(55.4)

Pituitary hormone co-staining

136

89(65.4)

 • TSH

136

57(41.9)

 • Prolactin

136

57(41.9)

 • ACTH

136

12(8.8)

 • FSH

136

4(2.9)

Granulation pattern

23

 

 • Densely

 

17(73.9)

 • Sparsely

 

6(26.1)

Cavernous sinus invasion

132

59(44.7)

Optic chiasm compression

132

43(32.6)