Factor | Total (N = 136) | |
---|---|---|
n | n (%) or Median [P25, P75] | |
Random GH level at Dx | 125 | 8.2[3.2,34.0] |
IGF-1 level at Dx | 134 | 769.0[567.0,956.0] |
2-h nadir post OGTT GH at Dx | 44 | 4.4[1.6,16.9] |
Most recent random GH level | 128 | 0.61[0.31,1.8] |
Most recent IGF-1 level | 134 | 205.5[155.0,281.0] |
Most recent 2-h nadir post OGTT GH | 32 | 0.32[0.19,0.90] |
Months between GH measures | 116 | 21.5[7.9,65.3] |
Months between IGF-1 measures | 131 | 34.7[12.8,87.9] |
Tumor size | 135 | |
• Macroadenoma | 111(82.2) | |
• Microadenoma | 24(17.8) | |
Tumor length/antero-posterior | 126 | 16.0[11.0,22.0] |
Tumor width/transverse | 116 | 16.0[10.5,20.0] |
Tumor height/craniocaudal | 105 | 14.0[10.0,20.0] |
GH staining | 136 | 124(91.2) |
GH staining type | 65 | |
• Rare | 29(44.6) | |
• Diffuse | 36(55.4) | |
Pituitary hormone co-staining | 136 | 89(65.4) |
• TSH | 136 | 57(41.9) |
• Prolactin | 136 | 57(41.9) |
• ACTH | 136 | 12(8.8) |
• FSH | 136 | 4(2.9) |
Granulation pattern | 23 | |
• Densely | 17(73.9) | |
• Sparsely | 6(26.1) | |
Cavernous sinus invasion | 132 | 59(44.7) |
Optic chiasm compression | 132 | 43(32.6) |