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Fig. 1 | Clinical Diabetes and Endocrinology

Fig. 1

From: The epidemiology, molecular pathogenesis, diagnosis, and treatment of maturity-onset diabetes of the young (MODY)

Fig. 1

A systematic approach to the diagnosis of MODY. Diagnosis of MODY is a stepwise process guided by a high index of suspicion, clinical assessment, diabetes-specific tests, and comprehensive genetic testing. BMI: body mass index; FPG: fasting plasma glucose; GAD-65: glutamic acid decarboxylase-65 autoantibodies; HbA1c: glycated hemoglobin; HDL: high density lipoprotein; IAA: insulin autoantibodies; IA-2A: tyrosine phosphatase-related islet antigen-2 autoantibodies; LDL: low density lipoprotein; OADs: oral antidiabetic drugs; OGTT: oral glucose tolerance test; RCAD: renal cysts and diabetes; T1DM: type 1 diabetes mellitus; T2DM: type 2 diabetes mellitus; ZnT8: zinc transporter 8 autoantibodies

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