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Table 3 Characterization by type of diabetes

From: Hypoglycemic episodes in hospitalized people with diabetes in Portugal: the HIPOS-WARD study

 

Total

(n = 176)

Type of diabetes

P-value

Type 1

(n = 18)

Type 2

(n = 152)

Hypoglycemia episode, n(%)

176 (100.0)

18 (10.2)

152 (86.4)

 

Gender (female), n(%)

97 (55.1)

6 (33.3)

88 (57.9)

0.048a

Age, median (min;max), (years)

75.0 (28;98)

49.5 (28.0;74.0)

78.0 (35.0;98.0)

< 0.001b

BMI, median (min;max), (kg/m2)

26.0 (4.6)

22.9 (18.4;31.6)

26.3 (15.6;38.8)

0.009d

Diabetes duration, median (min;max), (years)

11.0 (0.0;52.0)

22.0 (4.0;52.0)

10.0 (0.0;51.0)

0.001b

Diabetes management, n(%)

   

0.013a

 Solely managed by self

75 (42.6)

13 (72.2)

58 (38.2)

 

 Solely managed by other

52 (29.5)

1 (5.6)

50 (32.9)

 

 Occasional assistance

49 (27.8)

4 (22.2)

44 (28.9)

 

Usual diabetes outpatient care, n(%)f

   

0.001c

 Primary health care

111 (63.1)

4 (22.2)

104 (68.4)

 

 Hospital outpatient

45 (25.6)

11 (61.1)

31 (20.4)

 

 Private consultation

7 (4.0)

1 (5.6)

6 (3.9)

 

 Other

11 (6.3)

2 (11.1)

9 (5.9)

 

 Without follow-up

2 (1.1)

0 (0.0)

2 (1.3)

 

Chronic diabetes complications, n(%)f

 Eye complications

63 (50.0)

13 (81.3)

48 (46.2)

0.014e

 Neuropathy

29 (26.1)

7 (50.0)

19 (20.9)

0.040e

 Nephropathy

74 (47.4)

6 (37.5)

67 (49.6)

0.359a

 Lower limb complications

24 (15.9)

2 (11.8)

20 (15.6)

> 0.999e

 Known atherosclerotic disease

66 (47.8)

2 (14.3)

62 (51.7)

0.008a

  Coronary heart disease

32 (57.1)

2 (100.0)

29 (55.8)

 

  Cerebrovascular disease

31 (55.4)

1 (100.0)

30 (56.6)

 

  Motor complications

19 (33.3)

0 (0.0)

19 (35.8)

 

  Peripheral artery disease

25 (61.0)

1 (100.0)

24 (63.2)

 

  Other atherosclerotic dis

8 (21.1)

0 (0.0)

7 (20.0)

 

Previous hypoglycemia in last 12 months, n(%)

58 (47.5)

12 (85.7%)

42 (40.4%)

0.001a

Repeated hypo during hospitalization, n(%)

63 (36.0)

7 (41.2%)

51 (33.6%)

0.530a

Length of stay in ward, median (min;max)(h)

146.6 (1.6;1782.3)

   

Discharge destination, n(%)

   

0.052c

 Home

113 (64.2)

13 (72.2)

98 (64.5)

 

 Ambulatory

24 (13.6)

5 (27.8)

16 (10.5)

 

 Institution

30 (17.0)

0 (0.0)

29 (19.1)

 

 Other hospital

1 (0.6)

0 (0.0)

1 (0.7)

 

 Death

8 (4.5)

0 (0.0)

8 (5.3)

 

Risk factors for hypoglycemia, n(%)f

 > 75 years

87 (49.4)

0 (0.0)

86 (56.6)

< 0.001a

 Dementia

28 (16.7)

0 (0.0)

28 (19.0)

0.081e

 Major sensorial impairment

  Blindness

13 (7.4)

4 (23.5)

8 (5.3)

0.021e

  Deafness

6 (3.4)

1 (5.9)

5 (3.3)

0.476e

 Hypothyroidism

14 (10.1)

3 (18.8)

11 (9.4)

0.376e

 Adrenal failure

3 (2.2)

1 (7.1)

2 (1.7)

0.288e

 Severe renal failure

19 (38.0)

2 (40.0)

17 (38.6)

NA

 Hepatic failure

7 (4.1)

0 (0.0)

7 (4.7)

> 0.999e

 Cachexia/significant malnourishment

19 (10.9)

3 (17.6)

12 (7.9)

0.181e

 Brittle diabetes

21 (14.9)

6 (46.2)

13 (10.5)

0.003e

 Weaning of corticosteroid drugs

10 (5.8)

1 (5.9)

9 (6.0)

> 0.999e

 Previous hypo in the last 12 months

58 (47.5)

12 (85.7)

42 (40.4)

0.001a

 Lifestyle factors

  Irregular meals

52 (37.1)

8 (50.0)

41 (34.7)

0.235a

  Shift work

4 (2.4)

3 (18.8)

1 (0.7)

0.003e

  Other

7 (4.0)

1 (5.9)

5 (3.3)

0.478e

 Polypharmacy

147 (85.0)

7 (41.2)

135 (90.0)

< 0.001e

High risk for complications after the event

 Coronary heart disease

32 (25.0)

2 (14.3)

29 (26.4)

0.514e

 Cerebrovascular disease

31 (24.2)

1 (7.7)

30 (27.0)

0.182e

 Heart failure

48 (28.9)

0 (0.0)

48 (33.6)

0.004a

 Peripheral artery disease

25 (22.1)

1 (7.7)

24 (25.0)

0.291e

 Osteoporosis

8 (7.6)

1 (6.7)

7 (8.1)

> 0.999e

 Living alone

33 (18.8)

9 (50.0)

22 (14.5)

0.001e

  1. a Chi-square test; b Kruskal-Wallis test; c Monte Carlo approach; d ANOVA; e Fisher’s exact test; f Each patient can have more than one; Polyphramacy: > 5 distinct drugs, for one or more conditions