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Table 3 Summary of relative risk estimates (RR) (95 % CIs) for cohort studies that assess the association between depression and risk of MetS by gender, study population, continent, depression scales, MetS scales, and Age.

From: The relationship between depression and risk of metabolic syndrome: a meta‐analysis of observational studies

Subgroup Number of studies Summary Relative Risk (95 % CI) Between studies Between subgroups
I2 P heterogeneity Q Q P heterogeneity
Gender
Female
Male
Both
7
3
11
1.55 (1.23–1.94)
1.54 (1.11– 2.14)
1.23 (0.99–1.53)
89.04 %
93.61 %
94.47 %
< 0.001
< 0.001
< 0.001
59.64
31.28
89.61
2.40 0.30
Continents
America
Europe
9
12
1.46 (1.16–1.84)
1.28 (0.95–1.73)
98.51 %
92.41 %
< 0.001
< 0.001
99.79 95.84 0.45 0.50
Depression Scales
BDI
CES-D
Interview& DM
Other
5
8
5
3
1.50 (1.02–2.20)
1.34 (1.11–1.61)
1.45 (1.05–2.00)
1.10 (0.77 – 1.56)
91.39 %
77.66 %
99.21 %
38.96 %
< 0.001
< 0.001
< 0.001
0.19
46.48
31.34
98.27
3.28
1.81 0.61
MetS Scales
ATP III
IDF
19
2
1.41 (1.18–1.69)
1.13 (1.01–1.27)
96.94 %
14.80 %
< 0.001
0.28
588.0
1.17
4.14 0.04
Study Population
General
Patients
Other
19
1
1
1.46 (1.33–1.60)
-
-
97.78 %
-
-
< 0.001
-
-
810.7
-
-
1.32 0.52
Age
≤ 50 Year
> 50 Year
11
2
1.30 (1.13–1.49)
1.21 (1.13–1.44)
84.26 %
0.00 %
< 0.001
0.49
63.54
0.47
0.34 0.59
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