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Table 4 Biomarkers assessed as screening tool (number of OGTT avoidable)

From: The diagnostic indicators of gestational diabetes mellitus from second trimester to birth: a systematic review

Author—year

Ref N

Biomarker

Diagnostic criteria

Screening threshold value (sensitivity %)

Diagnostic cut-off value (specificity %)

OGTT avoided

Trujillo 2014

[15]

Fasting blood glucose (FBG)

IADPSG

A = 4.4 mmol⁄ l (96.9%)

B = 4.7 mmol⁄ l (92.5%)

5.1 mmol⁄ l (100%)

A = 61.3%

B = 81.3%

Ruetschi 2016

[31]

Fasting blood glucose (FBG)

IADPSG

4.4 mmol⁄ l (78.5%)

5.1 mmol/l (100%)

63.8%

Renz 2015

[36]

Glycated haemoglobin (HbA1C)

WHO 1999

5.8% (26.4%)

6.5% (100%)

B = 38%

Rajput 2012

[34]

Glycated haemoglobin (HbA1C)

ADA/IADPSG

5.45% (85.7%)

5.95% (97.2%)

61.8%