Table 3 Characteristics of subsequent GDM pregnancies with and without LGA and SGA. Data expressed as mean (SD), median (IQR) or n (%)
No LGA (n = 67) | LGA (n = 357) | p value | No SGA (n = 387) | SGA (n = 387) | p value | |
|---|---|---|---|---|---|---|
Age (years) | 33.7 (4.7) | 32.4 (5.6) | 0.02 | 33.5 (5.0) | 33.6 (4.0) | 0.94 |
Interval between pregnancies (years) | 3.0 (1.5) | 2.7 (1.7) | 0.28 | 2.8 (1.5) | 3.9 (2.1) | < 0.001 |
Booking-in weight (kg) | 67.0 (58.0,82.0) | 84.5 (69,105) | < 0.001 | 71.0 (59.3,88.0) | 65.0 (56.0,77.5) | 0.07 |
Weight change between pregnancies (kg) | 2.2 (5.4) | 4.7 (8.4) | 0.002 | 2.6 (6.1) | 2.4 (5.5) | 0.87 |
Booking-in BMI (kg/m2) | 26.5 (23.1,32.0) | 31.3 (26.9, 37.4) | < 0.001 | 27.1 (23,4,32.8) | 23.2 (25.8,31.6) | 0.46 |
Ethnicity (n,%) | 0.08 | 0.11 | ||||
-Europid | 38.4 | 50.7 | 41.6 | 27.0 | ||
-Non-Europid | 61.6 | 49.3 | 58.4 | 73.0 | ||
Parity (n,%) | 0.002 | 0.87 | ||||
1 | 55.9 | 35.8 | 52.3 | 56.8 | ||
2 | 25.6 | 28.4 | 26.2 | 24.3 | ||
> 2 | 18.9 | 35.8 | 21.5 | 18.9 | ||
Week of GDM diagnosis | 24.0 (17.0,27.0) | 23.5 (14.8,28.0) | 0.89 | 24.0 (16.0,27.0) | 20.0 (15.5,26.0) | 0.10 |
Early vs late GDM (n,%) | 0.42 | 0.22 | ||||
-Early | 42.7 | 48.5 | 42.6 | 54.1 | ||
-Late | 57.3 | 51.5 | 57.4 | 45.9 | ||
GTT- fasting glucose (mmol/L) | 4.9 (0.8) | 5.6 (1.5) | < 0.001 | 5.0 (1.0) | 4.7 (0.7) | 0.27 |
GTT- 2 h glucose (mmol/L) | 8.8 (1.6) | 9.7 (2.2) | 0.002 | 9.0 (1.7) | 8.8 (1.5) | 0.71 |
Medication required (%) | 0.17 | 0.72 | ||||
-Yes | 62.5 | 71.6 | 63.3 | 67.6 | ||
-No | 37.5 | 28.4 | 36.4 | 32.4 | ||
Same outcome in previous GDM preg | < 0.001 | < 0.001 | ||||
-Yes | 10.9 | 47.8 | 5.7 | 70.3 | ||
-No | 89.1 | 52.2 | 94.3 | 29.7 |