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Table 1 Baseline characteristics of ILI and SC cohorts of patients with type 1 diabetes and obesity

From: Multidisciplinary intensive lifestyle intervention improves markers of nonalcoholic fatty liver disease (NAFLD) in patients with type 1 diabetes and obesity: a retrospective matched-cohort study

 

ILI

(n = 77)

SC

(n = 77)

p value

Age (years)

43 ± 12

43 ± 12

NS

Female n (%)

50 (65)

50 (65)

NS

Diabetes duration (years)

22 ± 12

22 ± 9

NS

Weight (kg)

102.5 ± 17.3

100.9 ± 17.2

NS

BMI (kg/m2)

35.7 ± 5.0

35.3 ± 4.9

NS

ALT (U/L)

26.8 ± 20.2

21.6 ± 8.5

 < 0.05

AST (U/L)

22.4 ± 9.3

21.7 ± 12.0

NS

HbA1c (%)

8.2 ± 1.0

8.2 ± 0.9

NS

HSI

46.2 ± 6.1

44.9 ± 5.7

NS

HSI > 36 n (%)

77 (100)

75 (97.4)

NS

HSI < 30 n (%)

0 (0)

0 (0)

-

Total insulin dose (units/d)

69.9 ± 27.5

70.8 ± 27.4

NS

Weight-adjusted insulin dose (units/kg/d)

0.7 ± 0.2

0.7 ± 0.2

NS

Use of insulin pump therapy n (%)

49 (63.6)

36 (46.7)

 < 0.05

Systolic blood pressure (mmHg)

128 ± 14

126 ± 15

NS

Diastolic blood pressure (mmHg)

77 ± 8

77 ± 9

NS

Total Cholesterol (mg/dL)

169 ± 33

176 ± 26

NS

LDL-Cholesterol (mg/dL)

97 ± 32

97 ± 27

NS

HDL-Cholesterol (mg/dL)

55 ± 16

58 ± 17

NS

Triglycerides (mg/dL)

114 ± 88

121 ± 73

NS

  1. Data are mean ± SD
  2. ILI Intensive lifestyle intervention, SC Standard diabetes care, HSI Hepatic steatosis index, NAFLD Nonalcoholic fatty liver disease, ALT Alanine aminotransferase, AST Aspartate aminotransferase
  3. Student’s t-test or Pearson’s chi squared between groups