Table 2 Changes after one year of ILI or SC in patients with T1D and obesity
ILI (n = 77) | SC (n = 77) | p value† | |
|---|---|---|---|
Weight (kg) | -5.6 ± 2.7* | 1.6 ± 2.8 | < 0.001 |
BMI (kg/m2) | -1.8 ± 0.9* | 0.6 ± 0.8 | < 0.01 |
ALT (U/L) | -4.0 ± 2.5 | 1.9 ± 1.3 | < 0.05 |
AST (U/L) | -0.6 ± 1.1 | 0.2 ± 1.6 | NS |
HbA1c (%) | -0.33 ± 0.15* | -0.07 ± 0.16 | NS |
Total daily insulin dose (units/d) | -6.1 ± 4.2 | 1.3 ± 4.3 | < 0.01 |
Weight-adjusted insulin dose (units/kg/day) | -0.014 ± 0.020 | 0.004 ± 0.013 | NS |
Systolic blood pressure (mmHg) | -3.6 ± 2.1 | 0.4 ± 2.5 | NS |
Diastolic blood pressure (mmHg) | -1.9 ± 1.3 | -0.1 ± 1.4 | NS |
Total cholesterol (mg/dL) | 0.1 ± 6.3 | 0.9 ± 5.2 | NS |
LDL-cholesterol (mg/dL) | -4.7 ± 5.4 | 0.2 ± 3.4 | NS |
HDL-cholesterol (mg/dL) | 1.1 ± 2.9 | -0.9 ± 1.0 | NS |
Triglycerides (mg/dL) | -7.7 ± 13 | -0.4 ± 9.0 | NS |
HSI | -2.7 ± 1.1* | 0.6 ± 0.9 | < 0.001 |