Fig. 2

Effect of RAS modifying drugs on pulmonary outcomes. The association of diabetes diagnosis and incidence of infectious, inflammatory or structural outcomes events when compared to non-diabetic patients was measured using Cox analysis in this same model (a). The same parameters were measured using patients vaccinated for influenza compared to those who were not vaccinated and for patients taking statins at baseline compared to those not taking statins (a). These same analyses were done comparing the effect of initial choice of HTN therapy on infectious, inflammatory and structural outcomes; here we also corrected all of the baseline comorbidities; including T2DM, Flu-vaccine and statin use specifically (b). ****p < 0.0001