Fig. 1
From: Potential association of LMNA-associated generalized lipodystrophy with juvenile dermatomyositis
a Hematoxylin Eosin (HE) staining shows prominent perifascicular atrophy (asterisk). b HE staining highlights mononuclear infiltration around a blood vessel and infiltrating the endomysium. c CD163/CD4 immunostaining highlights several CD4 T-cells (red) in the perivascular and endomysial space with associated macrophages (brown) (d) MHC1 immunostaining shows abnormal sarcolemmal membrane overexpression in myocytes, note the normal control below should only highlight capillaries (e) C5b9 immunostaining highlights complement deposition in capillaries associated with affected fibers; note normal control does not show any capillary immunostain (f) Lamin A/C staining shows nuclear staining comparable to normal control. Scale bars: 50 μm