| |
Responders at week 24
|
---|
Yes
|
No
|
---|
Responders at Week 12
|
Yes
|
91%
|
9%
|
No
|
46%
|
54%
|
Predictive parameters
|
Odds ratio = 12.7 (P < 0.001)
|
Sensitivity = 85.9%
|
Specificity = 67.7%
|
Positive predictive value = 91.4%
|
Negative predictive value = 54.5%
|
- Sensitivity is the percentage of subsequent responders (HbA1c <7% or ≥ 1% reduction) correctly identified (true-positive rate). Specificity is the percentage of subsequent nonresponders (HbA1c ≥7% and < 1% reduction) correctly identified (true-negative rate). Positive predictive value is the percentage of subsequent responders among early responders. Negative predictive value is the percentage of subsequent nonresponders among early nonresponders. Abbreviation: HbA1c glycated hemoglobin