Table 1 Summary of treatment-related changes in human skeletal architecture. Only published studies that reported defined skeletal architectural indices were included in the Table

Bisphosphonates

4^(a)

2-2.5^(a)

↓,NS^(g)

↑ ^(g)

↑,NS^(g)

↓ ^(m)

NS^(m)

Denosumab

5.5^(b)

3^(b)

↓,NS^(h)

↑ ^(h)

↑ ^(h)

↓ ⁽ⁿ⁾

Teriparatide

9^(c)

3^(c)

↑ ^(f)

↑,NS⁽ⁱ⁾

↑,NS ⁽ⁱ⁾

↑,↓⁽ⁱ⁾

NS^(j)

↑ ^(k)

↑ ⁽⁰⁾

↑ ^(p)

↑ ^(p)

Abaloparatide

11^(d)

4^(d)

Romosozumab

13.5^(e)

6.5^(e)

↑ ^(l)

↑ ^(l)

↑ ^(l)