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Table 1 Patient characteristics

From: Pheochromocytoma and Paraganglioma in Neurofibromatosis type 1: frequent surgeries and cardiovascular crises indicate the need for screening

Total number of patients 17
Gender (male/female) 9/8
Average age at diagnosis (years, range) 41 (20–62)
Means of diagnosis (biochemical/imaging/unknown) 5/11/1
Incidental Imaging finding (yes/no) 8/9
Presence of cardiovascular crisis (# patients) 6
Hypertension (yes/no/unknown) 9/8/0
Tachycardia, HR > 100 (yes/no/unknown) 4/5/5
Both HTN & Tachycardia (yes/no/unknown) 2/10/5
Number antihypertensive medications (average, range) 1 (0–4)
Elevated plasma or urine catecholamines or metanephrines (yes/no/unknown) 16/0/1
Level of metanephrine elevation (times upper limit of normal). (mean/median/range)  
UM
UNM
PM
PNM
12.6/ 5.2/ (0.5–19.0)
4.6/ 2.7/ (0.6–3.5)
6.7/ 3.6/ (0.7–16.8)
3.2/ 2.0/ (1.4–10.2)
Elevations in both metanephrines & normetanephrines (yes/no/unknown) 10/1/6
MIBG scan (pos/neg/not done) 9/0/8
  1. Abbreviations: HTN hypertension, HR heart rate, UM (urine metanephrine, reference range < 300 mcg/24 h), UNM (urine normetanephrine, reference range < 800 mcg/24 h), PM (plasma metanephrine, reference range < 0.5 nmol/L), PNM (plasma normetanephrine, reference range < 0.9 nmol/L), MIBG meta-iodobenzylguanidine