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Table 1 Characteristics and evolution of acromegalic and control patients (absolute values and percentages)

From: Acromegaly and thyroid cancer: analysis of evolution in a series of patients

Patients

Acro

(n = 23)

Controls

(n = 92)

p-value

Gender

[Female: n (%)]

18 (78.3)

82 (89.1)

0.29

Mean age at DTC diagnosis

(years ± SD)

49.3 ± 13.9

47.5 ± 16.5

0.31

Insulin resistance

[n (%)]

9 (39.1)

10 (10.9)

0.003

History of other cancer

[n (%)]

2 (8.7)

3 (3.3)

0.56

Histologya

[n (%)]

 clPTC

16 (69.6)

73 (79.3)

0.43

 fvPTC

7 (30.4)

19 (20.7)

Mean tumor size

[mm, (range)]

15.2 (4–35)

14.6 (3–60)

0.76

Lymphadenectomy [n (%)]

8 (34.8)

15 (16.3)

0.09

Node metastases [n (%)]

5 (62.5)

10 (66.7)

1

Radioiodine ablation [n (%)]

21 (91.3)

63 (68.5)

0.052

Median iodine dose [mCi, (range)]

100 (30–300)

100 (30–150)

0.53

Median time of follow-up

[months, (range)]

36.5 (6–120)

49.5 (6–219)

0.14

Follow-up responseb

[n (%)]

NED

19 (82.7)

60 (65.2)

0.36

Ind

2 (8.7)

22 (23.9)

BI

1 (4.3)

3 (3.3)

SI

1 (4.3)

7 (7.6)

  1. aHistology: clPTC classic papillary thyroid carcinoma. fvPTC follicular variant papillary thyroid carcinoma
  2. bFollow-up response: NED no evidence of disease, Ind indeterminate, BI biochemical incomplete, SI structural incomplete