Table 2 Comparison of clinical variables before and after the intervention in the studied groups

Mean pain score

Before

6.9±1.8

6.3±1.85

0.36

fourth week

5.0±1.1

4.0±1.5

0.43

Eighth week

2.3±1.4

1.5±1.5

P- value

<0.001

<0.001

Mean sleep score

Before

4.82±2.2

6.11±2.2

0.43

fourth week

6.9±1.9

8.0±1.2

0.95

Eighth week

9.42±0.7

9.7±0.5

P- value

<0.001

<0.001

PGIC (%)

1

-

40

42

-

2

-

38

37

-

3

-

20

20

-

4

-

2

1

-

5

-

0

0

-

CGIC (%)

1

-

41

43

-

2

-

38

39

-

3

-

19

17

-

4

-

2

1

-

5

-

0

0

-

Side effects (N (%))

 Drowsiness

After

11 (21.6)

0

 Nausea

3 (6)

8 (15.7)

0.001

 Dyspepsia

1 (2)

5 (9.8)

 No side effects

28 (54.9)

38 (74.5)