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  1. Diabetic foot ulcers (DFU) are a costly complication of diabetes mellitus (DM), with significant implications for the patient and the healthcare professionals that treat them. The primary objective of this stu...

    Authors: Brennen O’Dell, Gary Rothenberg, Crystal Holmes, Sari Priesand, Kara Mizokami-Stout, Eric J. Brandt and Brian M. Schmidt
    Citation: Clinical Diabetes and Endocrinology 2024 10:19
    Content type: Research article Published on:

  2. Gestational Diabetes Mellitus (GDM) poses significant health risks to mothers and infants. Early prediction and effective management are crucial to improving outcomes. Machine learning techniques have emerged ...

    Authors: Emmanuel Kokori, Gbolahan Olatunji, Nicholas Aderinto, Ifeanyichukwu Muogbo, Ikponmwosa Jude Ogieuhi, David Isarinade, Bonaventure Ukoaka, Ayodeji Akinmeji, Irene Ajayi, Ezenwoba Chidiogo, Owolabi Samuel, Habeebat Nurudeen-Busari, Abdulbasit Opeyemi Muili and David B. Olawade
    Citation: Clinical Diabetes and Endocrinology 2024 10:18
    Content type: Review article Published on:

  3. Sarcopenia and sarcopenic obesity are growing concerns associated with increasing diabetes incidence, but data from Indian diabetic cohorts are limited. This study examined the prevalence and clinical factors ...

    Authors: Yogesh M., Monika G. Patel, Hardik Harshadbhai Makwana and Hardikkumar Kalariya
    Citation: Clinical Diabetes and Endocrinology 2024 10:22
    Content type: Research article Published on:

  4. Diabetes presenting in young adults is often challenging to classify. Diabetic ketoacidosis is typically seen in autoimmune type 1 diabetes mellitus and more rarely in young onset type 2 diabetes mellitus. Bet...

    Authors: Xi May Zhen, Stephen M. Twigg, Ted Wu, Eddy Tabet, Margaret J. McGill, Maria Constantino, Amali Mallawaarachchi, Connie Luo, Senthil Thillainadesan, Yusof Rahman and Jencia Wong
    Citation: Clinical Diabetes and Endocrinology 2024 10:17
    Content type: Review article Published on:

  5. Type 1 Diabetes (T1D) is associated with increased risk of fractures, worsened by presence of microvascular complications. This study’s objective is to determine the impact of progressive decline in estimated ...

    Authors: Funmbi Babalola, Jill Hamilton, Michael Zappitelli, Yesmino Elia, Jacqueline Curtis, Rahim Moineddin and Farid H. Mahmud
    Citation: Clinical Diabetes and Endocrinology 2024 10:12
    Content type: Research article Published on:

  6. Hypertension (HT) is an orchestrator of atherosclerotic cardiovascular disease (ASCVD) in people living with type 2 diabetes (T2D). Control of systolic blood pressure (SBP) and HT as a whole is suboptimal in d...

    Authors: William Lumu, Silver Bahendeka, Davis Kibirige, Ronald Wesonga and Ronald Kasoma Mutebi
    Citation: Clinical Diabetes and Endocrinology 2024 10:16
    Content type: Research article Published on:

  7. This mini-narrative review explores the relationship between diabetes and dementia, focusing on the potential mitigating role of metformin in reducing cognitive decline among individuals with type 2 diabetes. ...

    Authors: Nicholas Aderinto, Gbolahan Olatunji, Emmanuel Kokori, Praise Fawehinmi, Abdulrahmon Moradeyo, Stephen Igwe, Rebecca Ojabo, Badrudeen Olalekan Alabi, Emmanuel Chuka Okafor, Damilola Ologbe, Ayobami Olafimihan and David B. Olawade
    Citation: Clinical Diabetes and Endocrinology 2024 10:10
    Content type: Review article Published on:

  8. Despite its high prevalence in the western world metabolic dysfunction-associated steatotic liver disease (MASLD) does not benefit from targeted pharmacological therapy. We measured healthcare utilisation and ...

    Authors: Arnaud Nze Ossima, Angélique Brzustowski, Valérie Paradis, Bernard Van Beers, Catherine Postic, Cédric Laouénan, Stanislas Pol, Laurent Castéra, Jean-François Gautier, Sebastien Czernichow, Anais Vallet-Pichard, Etienne Larger, Lawrence Serfaty, Marie Zins, Dominique Valla and Isabelle Durand Zaleski
    Citation: Clinical Diabetes and Endocrinology 2024 10:9
    Content type: Research article Published on:

  9. Painful diabetic neuropathy (PDN) is highly prevalent and annoyingly in patients with diabetes. The aim of this study was to investigate the effects of oral N-acetylcysteine (NAC) compared to pregabalin in PDN.

    Authors: Firozeh Sajedi, Arman Abdi, Maryam Mehrpooya, Vida Faramarzi, Younes Mohammadi and Fateme Sheida
    Citation: Clinical Diabetes and Endocrinology 2024 10:15
    Content type: Research article Published on:

  11. Most of the cases of hyperglycemia during pregnancy are attributed to gestational diabetes mellitus (GDM) (75–90%). Women diagnosed with GDM are at an increased risk for complications during pregnancy and deli...

    Authors: Yehia Moustafa Ghanem, Yasser El Kassar, May Mohamed Magdy, Mohamed Amara and Noha Gaber Amin
    Citation: Clinical Diabetes and Endocrinology 2024 10:7
    Content type: Research article Published on:

  12. Dipeptidyl peptidase-4 (DPP-4) inhibitors are a class of drugs that enhance the incretin-insulin pathway and offer effective glycemic control in type 2 diabetes mellitus. However, these drugs may be associated...

    Authors: Shirin Zaresharifi, Mahtab Niroomand, Sarina Borran and Sahar Dadkhahfar
    Citation: Clinical Diabetes and Endocrinology 2024 10:6
    Content type: Review article Published on:

  13. Type 1 diabetes mellitus one of the biggest health concerns around the world, is difficult to manage during adolescence. Among the non-medical methods of controlling this disease is empowerment through self-ef...

    Authors: Jamalodin Begjani, Akram Sadat Sadat Hosseini, Hedieh Saneifard and Vida Rahimi Hasanabad
    Citation: Clinical Diabetes and Endocrinology 2024 10:14
    Content type: Research article Published on:

  14. Heterozygous insulin receptor mutations (INSR) are associated with insulin resistance, hyperglycaemia and hyperinsulinaemic hypoglycaemia in addition to hyperandrogenism and oligomenorrhoea in women. Numerous ...

    Authors: Mairéad T. Crowley, Eirena Goulden, Begona Sanchez-Lechuga, Aileen Fleming, Maria Kennelly, Ciara McDonnell and Maria M. Byrne
    Citation: Clinical Diabetes and Endocrinology 2024 10:5
    Content type: Case report Published on:

  15. Social determinants of health (SDOH) research demonstrates poverty, access to healthcare, discrimination, and environmental factors influence health outcomes. Several models are commonly used to assess SDOH, y...

    Authors: Zach W. Cooper, Orion Mowbray and Leslie Johnson
    Citation: Clinical Diabetes and Endocrinology 2024 10:4
    Content type: Research article Published on:

  16. Due to the progressive decline in β-cell function, it is often necessary to utilize multiple agents with complementary mechanisms of action to address various facets and achieve glycemic control. Thus, this st...

    Authors: Mondal Aashish, Naskar Arindam, Sheelu Shafiq Siddiqi, Deepak Bhosle, V. J. Mallikarjuna, Dange Amol, Sorate Sanket, Gavali Omkar, Patel Parth, Hasnani Dhruvi, Prasad Durga, Dalwadi Pradeep, Kumar Suresh, Pathak Vaishali, Chaudhari Mayura, Basu Indraneel…
    Citation: Clinical Diabetes and Endocrinology 2024 10:3
    Content type: Research article Published on:

  17. Identification of modifiable risk factors for Alzheimer’s Disease (AD) onset is an important aspect of controlling the burden imposed by this disease on an increasing number of older U.S. adults. Graves diseas...

    Authors: Arseniy Pavlovich Yashkin, Stanislav Kolpakov, Svetlana Ukraintseva, Anatoliy Yashin and Igor Akushevich
    Citation: Clinical Diabetes and Endocrinology 2024 10:11
    Content type: Research article Published on:

  18. Glucocorticoid (GC)-induced hyperglycemia is a frequent issue, however there are no specific guidelines for this diabetes subtype. Although treat-to-target insulin is recommended in general to correct hypergly...

    Authors: Tristan Struja, Neele Nitritz, Islay Alexander, Kevin Kupferschmid, Jason F. Hafner, Carlos C. Spagnuolo, Philipp Schuetz, Beat Mueller and Claudine A. Blum
    Citation: Clinical Diabetes and Endocrinology 2024 10:8
    Content type: Research article Published on:

  19. Professional guidelines recommend an HbA1c < 7% for most people with diabetes and < 8.5% for those with relaxed glycemic goals. However, many people with type 2 diabetes mellitus (T2DM) are unable to achieve t...

    Authors: Judy Z. Louie, Dov Shiffman, Charles M. Rowland, Norma S. Kenyon, Ernesto Bernal-Mizrachi, Michael J. McPhaul and Rajesh Garg
    Citation: Clinical Diabetes and Endocrinology 2024 10:2
    Content type: Research article Published on:

  20. The objective of this meta-analysis was to investigate the association between plasma bilirubin levels and the incidence of metabolic syndrome and diabetes mellitus across all populations.

    Authors: Maziar Nikouei, Mojtaba Cheraghi, Faezeh Ghaempanah, Parisa Kohneposhi, Nadia Saniee, Sirous Hemmatpour and Yousef Moradi
    Citation: Clinical Diabetes and Endocrinology 2024 10:1
    Content type: Review article Published on:

  22. Obesity has reached epidemic proportions in children and adolescents in the United States. Children’s behaviors are strongly influenced by parental behaviors, and weight loss in parents is positively associate...

    Authors: Namratha Atluri, Joshua Thariath, Laura N. McEwen, Wen Ye, MinKyoung Song and William H. Herman
    Citation: Clinical Diabetes and Endocrinology 2023 9:8
    Content type: Research article Published on:

  23. Homeostasis model assessment for insulin resistance (HOMA-IR) is a biomarker for type 2 diabetes mellitus (T2DM). However, the role of HOMA-IR in the non-diabetic is unclear. This study aimed to determine whet...

    Authors: Jibeom Lee, Moon-hyun Kim, Ji-Yong Jang and Chang-Myung Oh
    Citation: Clinical Diabetes and Endocrinology 2023 9:7
    Content type: Research article Published on:

  25. Pituitary adenomas (PPAs) are uncommon in childhood and adolescence, accounting for 2–6% of all intracranial neoplasms. Delayed puberty, growth retardation, galactorrhea and weight gain are common features at ...

    Authors: Cristina Aguilar-Riera, María Clemente, Núria González-Llorens, Eduard Mogas, Ariadna Campos-Martorell, Anna Fàbregas, Betina Biagetti, Elida Vázquez and Diego Yeste
    Citation: Clinical Diabetes and Endocrinology 2023 9:5
    Content type: Case report Published on:

  27. The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing among patients with type 1 diabetes (T1D) paralleling the increasing prevalence of obesity among this population. However, little is kn...

    Authors: Shaheen Tomah, Tareq Salah, Marwa Al-Badri, Shilton Dhaver, Hannah Gardner, Mhd Wael Tasabehji and Osama Hamdy
    Citation: Clinical Diabetes and Endocrinology 2023 9:3
    Content type: Research article Published on:

  28. The risk of adverse outcomes in recurrent GDM pregnancy has not been well documented, particularly in women who have already had an adverse outcome. The aim of this study was to compare the risk of recurrent a...

    Authors: Sue Lynn Lau, Alex Chung, Joanna Kao, Susan Hendon, Wendy Hawke and Sue Mei Lau
    Citation: Clinical Diabetes and Endocrinology 2023 9:2
    Content type: Research article Published on:

  29. Undiagnosed type 2 diabetes is common and can lead to unrecognized health complications. Given that earlier detection can reduce the damage to vital organs, it is important for all persons to be able to make t...

    Authors: María Teresa Muñoz Sastre, Paul Clay Sorum, Lonzozou Kpanake and Etienne Mullet
    Citation: Clinical Diabetes and Endocrinology 2023 9:1
    Content type: Research Article Published on:

  30. Genetic alterations and high levels of the vascular endothelial growth factor (VEGF) are presumptive risk factors for differentiated thyroid cancer (DTC).

    Authors: Mohamad Mohsen Motawea, Maysaa El Sayed Zaki, Maha Saif, Asmaa Osama BS Osman and Aml Mohamed Nada
    Citation: Clinical Diabetes and Endocrinology 2022 8:9
    Content type: Research article Published on:

  31. Hypoglycemic syndrome is a potentially life-threatening condition that can lead to the disruption of brain and internal organ functions, and in severe cases to irreparable consequences or death. Factitious hyp...

    Authors: Marina Yukina, Ilana Katsobashvili, Nadezhda Platonova, Ekaterina Troshina and Galina Mel’nichenko
    Citation: Clinical Diabetes and Endocrinology 2022 8:8
    Content type: Case report Published on:

  32. Several systemic and sociodemographic factors have been associated with the development and progression of diabetic retinopathy (DR). However, there is limited investigation of the potential role sociodemograp...

    Authors: Chan Tran N. Nguyen, Matheos Yosef, Shokoufeh Khalatbari and Anjali R. Shah
    Citation: Clinical Diabetes and Endocrinology 2022 8:7
    Content type: Research article Published on:

  33. Insulin edema is a rare complication which can present after initiation or intensification of insulin therapy in people with diabetes. Initiation of closed-loop hybrid insulin pump therapy can result in rapid ...

    Authors: Mostafa Vasigh and Rachel Hopkins
    Citation: Clinical Diabetes and Endocrinology 2022 8:6
    Content type: Case report Published on:

  34. This study aimed to compare the effects of Linagliptin and Empagliflozin on renal function and glycaemic control in patients with type 2 diabetes mellitus (DM).

    Authors: Mohammad Amin Mohammad zadeh Gharabaghi, Mohammad Reza Rezvanfar, Nasser Saeedi, Faezeh Aghajani, Mohammad Alirezaei, Pourya Yarahmadi and Amin Nakhostin-Ansari
    Citation: Clinical Diabetes and Endocrinology 2022 8:5
    Content type: Research article Published on:

  35. Many patients with severe COVID-19 have impaired glucose tolerance, and steroid therapy is a standard treatment. Thus, good glycemic control is important and correlates with better patient outcomes. We began u...

    Authors: Yoshihito Takahashi, Hiroshi Matsuura, Hisaya Domi and Hitoshi Yamamura
    Citation: Clinical Diabetes and Endocrinology 2022 8:4
    Content type: Research article Published on:

  36. Hyperinsulinemic hypoglycemia is the most common cause of severe and persistent hypoglycemia in neonates and children. It is a heterogeneous condition with dysregulated insulin secretion, which persists in the...

    Authors: M. G. Castillo-López, M. F. Fernandez, N. Sforza, N. C. Barbás, F. Pattin, G. Mendez, F. Ogresta, I. Gondolesi, P. Barros Schelotto, C. Musso and G. E. Gondolesi
    Citation: Clinical Diabetes and Endocrinology 2022 8:3
    Content type: Case report Published on:

  37. The prevalence of Gestational Diabetes Mellitus (GDM) varies worldwide among racial and ethnic groups, population characteristics (eg, average age and body mass index (BMI) of pregnant women), testing method, ...

    Authors: Balkachew Nigatu, Tigist Workneh, Thomas Mekuria, Helen Yifter, Yeshiwondim Mamuye and Addisu Gize
    Citation: Clinical Diabetes and Endocrinology 2022 8:2
    Content type: Research article Published on:

  38. The increase in growth hormone (GH) secretion during a prolonged fast stimulates lipolytic rate, thereby augmenting the mobilization of endogenous energy at a time when fuel availability is very low.

    Authors: N. Goldenberg, J. F. Horowitz, A. Gorgey, A. Sakharova and A. L. Barkan
    Citation: Clinical Diabetes and Endocrinology 2022 8:1
    Content type: Research article Published on:

  39. Individuals with multiple islet autoantibodies are at increased risk for clinical type 1 diabetes and may proceed gradually from stage to stage complicating the recruitment to secondary prevention studies. We ...

    Authors: Maria Månsson Martinez, Lampros Spiliopoulos, Falastin Salami, Daniel Agardh, Jorma Toppari, Åke Lernmark, Jukka Kero, Riitta Veijola, Päivi Tossavainen, Sauli Palmu, Markus Lundgren, Henrik Borg, Anastasia Katsarou, Helena Elding Larsson, Mikael Knip, Marlena Maziarz…
    Citation: Clinical Diabetes and Endocrinology 2022 7:23
    Content type: Research article Published on:

  41. Type 2 diabetes reversal has been viewed in the literature primarily as a dichotomous event (reversed or not reversed), even though this viewpoint may not be optimal for clinicians or patients. This cohort stu...

    Authors: Paramesh Shamanna, Shashank Joshi, Lisa Shah, Mala Dharmalingam, Banshi Saboo, Jahangir Mohammed, Maluk Mohamed, Terrence Poon, Nathan Kleinman, Mohamed Thajudeen and Ashok Keshavamurthy
    Citation: Clinical Diabetes and Endocrinology 2021 7:21
    Content type: Research article Published on:

  42. Acute kidney injury (AKI) due to Diabetic Ketoacidosis (DKA) is rather common. Novel biomarkers to diagnose AKI are being increasingly used in different settings. The use of urinary Neutrophil Gelatinase-Assoc...

    Authors: Vijai Williams, Muralidharan Jayashree, Karthi Nallasamy, Devi Dayal, Amit Rawat and Savita Verma Attri
    Citation: Clinical Diabetes and Endocrinology 2021 7:20
    Content type: Research article Published on:

  43. Gestational diabetes mellitus (GDM) is glucose intolerance first recognised during pregnancy. Both modalities and thresholds of the GDM diagnostic test, the Oral Glucose Tolerance Test (OGTT), have varied wide...

    Authors: Daria Di Filippo, Thiyasha Wanniarachchi, Daniel Wei, Jennifer J. Yang, Aoife Mc Sweeney, Alys Havard, Amanda Henry and Alec Welsh
    Citation: Clinical Diabetes and Endocrinology 2021 7:19
    Content type: Review article Published on:

  44. Patients with lipodystrophy are at high risk for chronic complications of diabetes. Recently, we have reported 18 diabetic foot ulcer episodes in 9 subjects with lipodystrophy. This current study aims to deter...

    Authors: O Saydam, B Ozgen Saydam, SC Adiyaman, M Sonmez Ince, MA Eren, FE Keskin, H Bilen, M Dagdeviren, S Kaya, G Akinci, A Balci, C Altay, F Bayraktar, EA Oral and B Akinci
    Citation: Clinical Diabetes and Endocrinology 2021 7:18
    Content type: Research article Published on:

  45. There is conflicting evidence regarding an association between gonadotropin releasing hormone analogue (GnRHa) therapy and polycystic ovary syndrome (PCOS). This study aimed to compare the prevalence of endocr...

    Authors: Gilad Karavani, Henry H. Chill, Natali Schachter-Safrai, Gan Lomnitz, David Gillis and Dvora Bauman
    Citation: Clinical Diabetes and Endocrinology 2021 7:14
    Content type: Research article Published on:

  46. The study characterizes safety, tolerability, pharmacokinetic and pharmacodynamic profiles of single rising doses of the 11beta-hydroxysteroid dehydrogenase-1 (11beta-HSD1) inhibitor BI 187004 in healthy men w...

    Authors: Susanna Bianzano, Tim Heise, Arvid Jungnik, Cornelia Schepers, Corinna Schölch and Ulrike Gräfe-Mody
    Citation: Clinical Diabetes and Endocrinology 2021 7:16
    Content type: Research article Published on:

  47. Diabetic ketoacidosis (DKA) is an emergency with high morbidity and mortality. This study examined patient factors associated with hospitalization for recurrent DKA.

    Authors: Ryan Lyerla, Brianna Johnson-Rabbett, Almoutaz Shakally, Rekha Magar, Hind Alameddine and Lisa Fish
    Citation: Clinical Diabetes and Endocrinology 2021 7:13
    Content type: Research article Published on:

  48. Diabetic retinopathy is the most frequent complication of Diabetes Mellitus and remains the leading cause of preventable blindness. However, there are limited studies on the determinants of diabetic retinopath...

    Authors: Kalid Seid, Temamen Tesfaye, Admasu Belay and Hayat Mohammed
    Citation: Clinical Diabetes and Endocrinology 2021 7:12
    Content type: Research article Published on:

  49. Hyperglycemia is the most common side-effect of phosphatidylinositol 3-kinase (PI3K) inhibitors that are approved for the treatment of some advanced or metastatic breast cancers. This side-effect is likely due...

    Authors: Nicolas Sahakian, Lauranne Cattieuw, Clotilde Ramillon-Cury, Audrey Bégu-Le Corroller, Pascale Silvestre-Aillaud, Sophie Béliard and René Valéro
    Citation: Clinical Diabetes and Endocrinology 2021 7:17
    Content type: Case report Published on:

  50. The relationship between H. pylori infection and obesity development has remained controversial among various studies. The aim of this study was to clarify the pooled effect of H. pylori infection on the devel...

    Authors: Ali Baradaran, Hojat Dehghanbanadaki, Sara Naderpour, Leila Mohammadi Pirkashani, Abdolhalim Rajabi, Roya Rashti, Sevda Riahifar and Yousef Moradi
    Citation: Clinical Diabetes and Endocrinology 2021 7:15
    Content type: Research article Published on:
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Clinical Diabetes and Endocrinology

ISSN: 2055-8260

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