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  1. Content type: Review article

    Globally, the burden of diabetes mellitus has increased to epidemic proportions. Estimates from the International Diabetes Federation predict that the greatest future increase in the prevalence of diabetes mel...

    Authors: Davis Kibirige, William Lumu, Angus G. Jones, Liam Smeeth, Andrew T. Hattersley and Moffat J. Nyirenda

    Citation: Clinical Diabetes and Endocrinology 2019 5:2

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  2. Content type: Review article

    Since 2011 six immune checkpoint inhibitors (ICI) have been approved to treat patients with many advanced solid tumor and hematological malignancies to improve their prognosis. Case reports of their endocrine ...

    Authors: Meng H. Tan, Ravi Iyengar, Kara Mizokami-Stout, Sarah Yentz, Mark P. MacEachern, Li Yan Shen, Bruce Redman and Roma Gianchandani

    Citation: Clinical Diabetes and Endocrinology 2019 5:1

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  3. Content type: Case report

    Celiac disease (CD) is an autoimmune disorder related to the gluten and can be also associated with some other endocrine disorders such as type 1 diabetes and thyroid disease. Gluten exposure in CD may have es...

    Authors: Azita Ganji and Meysam Moghbeli

    Citation: Clinical Diabetes and Endocrinology 2018 4:24

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  4. Content type: Case report

    Cortisol resistance syndrome is a very rare condition characterized by high cortisol levels, but without any clinical features of Cushing’s syndrome. Our objective is to present such a case.

    Authors: Ved V. Gossain, Mohammad El-Rifai, Preethi Krishnan and Bhavini Bhavsar

    Citation: Clinical Diabetes and Endocrinology 2018 4:23

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  5. Content type: Commentary

    Sri Lanka is experiencing a rapid increase in the number of people with diabetes mellitus (DM) due to population growth and aging. Physician shortages, outdated technology, and insufficient health education ha...

    Authors: Anjan K. Saha, Naresh Gunaratnam, Rashmi Patil, Monica Choo, Devika P. Bagchi, Ekta Jhaveri, Jennifer Wyckoff, Ganeika Bahu, Ulysses Balis, Paul Clyde and William H. Herman

    Citation: Clinical Diabetes and Endocrinology 2018 4:22

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  6. Content type: Research article

    Limited data are available regarding the level of adherence and barriers to dietary recommendations in individuals with type 2 diabetes in Africa including Ethiopia. Therefore, this study aimed at assessing th...

    Authors: Asnakew Achaw Ayele, Yohannes Kelifa Emiru, Sofonyas Abebaw Tiruneh, Belete Achamyelew Ayele, Alemayehu Digssie Gebremariam and Henok Getachew Tegegn

    Citation: Clinical Diabetes and Endocrinology 2018 4:21

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  7. Content type: Research article

    Diabetes management is influenced by a number of factors beyond the individual-level. This study examined how neighborhood social disorganization (i.e., neighborhoods characterized by high economic disadvantag...

    Authors: Sarah D. Kowitt, Katrina E. Donahue, Edwin B. Fisher, Madeline Mitchell and Laura A. Young

    Citation: Clinical Diabetes and Endocrinology 2018 4:19

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  8. Content type: Review article

    The measurement of circulating concentrations of growth hormone (GH) is an indispensable tool in the diagnosis of both GH deficiency and GH excess. GH is a heterogeneous protein composed of several molecular i...

    Authors: Júnia Ribeiro de Oliveira Longo Schweizer, Antônio Ribeiro-Oliveira Jr and Martin Bidlingmaier

    Citation: Clinical Diabetes and Endocrinology 2018 4:18

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  9. Content type: Review article

    Neuroendocrine tumors (NETs) are rare neoplasms, with an estimated annual incidence of ~ 6.9/100,000. NETs arise throughout the body from cells of the diffuse endocrine system. More than half originate from en...

    Authors: Inbal Uri and Simona Grozinsky-Glasberg

    Citation: Clinical Diabetes and Endocrinology 2018 4:16

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  10. Content type: Research article

    Pheochromocytomas and Paragangliomas (PCC/PGL) are rare endocrine tumors that are mostly benign, but often hormone producing, causing significant morbidity and mortality due to excess catecholamine secretion a...

    Authors: Elisabeth Joye Petr and Tobias Else

    Citation: Clinical Diabetes and Endocrinology 2018 4:15

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  11. Content type: Research article

    The long-term effect of weight reduction on skeletal health is not well understood. The purpose of this study was to examine the impact of an intensive medical weight loss intervention using very low energy di...

    Authors: Palak Choksi, Amy Rothberg, Andrew Kraftson, Nicole Miller, Katherine Zurales, Charles Burant, Catherine Van Poznak and Mark Peterson

    Citation: Clinical Diabetes and Endocrinology 2018 4:14

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  12. Content type: Case report

    Malignant struma ovarii is an ovarian teratoma containing at least 50% thyroid tissue which has the potential to metastasize and produce thyroid hormone. Given its rarity, management strategies are not well-es...

    Authors: Corey J. Lager, Ronald J. Koenig, Richard W. Lieberman and Anca M. Avram

    Citation: Clinical Diabetes and Endocrinology 2018 4:13

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  13. Content type: Research article

    Therapy for Type 2 diabetes (T2D) has been transformed by the introduction of newer agents like Glucagon like Peptide Receptor Agonists (GLP-1RA) and Sodium-glucose linked transporter inhibitors (SGLT2i). Howe...

    Authors: S. Ghosal and B. Sinha

    Citation: Clinical Diabetes and Endocrinology 2018 4:11

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  14. Content type: Research article

    To identify baseline/clinical characteristics associated with clinically meaningful responses to insulin glargine 100 U/mL (IGlar) in insulin-naive people with type 2 diabetes mellitus (T2DM).

    Authors: M. H. Cummings, D. Cao, I. Hadjiyianni, L. L. Ilag and M. H. Tan

    Citation: Clinical Diabetes and Endocrinology 2018 4:10

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  15. Content type: Review article

    Skeletal fractures can result when there are co-morbid conditions that negatively impact bone strength. Fractures represent an important source of morbidity and mortality, especially in older populations. Diab...

    Authors: Rodrigo J. Valderrábano and Maria I. Linares

    Citation: Clinical Diabetes and Endocrinology 2018 4:9

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  16. Content type: Research article

    The Community Healthy Activities Model Program for Seniors (CHAMPS) survey, summarized into weekly caloric expenditures, is a common physical activity (PA) assessment tool among older adults. Specific types of...

    Authors: Pearl G. Lee, Jinkyung Ha, Caroline S. Blaum, Kimberlee Gretebeck and Neil B. Alexander

    Citation: Clinical Diabetes and Endocrinology 2018 4:7

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  17. Content type: Case report

    Juvenile dermatomyositis (JDM) is an auto-immune muscle disease which presents with skin manifestations and muscle weakness. At least 10% of the patients with JDM present with acquired lipodystrophy. Laminopat...

    Authors: Melis Sahinoz, Shafaq Khairi, Ashley Cuttitta, Graham F. Brady, Amit Rupani, Rasimcan Meral, Marwan K. Tayeh, Peedikayil Thomas, Meredith Riebschleger, Sandra Camelo-Piragua, Jeffrey W. Innis, M. Bishr Omary, Daniel E. Michele and Elif A. Oral

    Citation: Clinical Diabetes and Endocrinology 2018 4:6

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  18. Content type: Research article

    In a randomized controlled trial of 628 Chinese patients with type 2 diabetes receiving multidisciplinary care in the Joint Asia Diabetes Evaluation (JADE) Progam, 372 were randomized to receive additional tel...

    Authors: Roseanne O. Yeung, Jing-Heng Cai, Yuying Zhang, Andrea O. Luk, Jun-Hao Pan, Junmei Yin, Risa Ozaki, Alice P. S. Kong, Ronald Ma, Wing-Yee So, Chiu Chi Tsang, K. P. Lau, Edwin Fisher, Williams Goggins, Brian Oldenburg and Julianna Chan

    Citation: Clinical Diabetes and Endocrinology 2018 4:5

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  19. Content type: Review article

    Graves’ hyperthyroidism affects 0.2% of pregnant women. Establishing the correct diagnosis and effectively managing Graves’ hyperthyroidism in pregnancy remains a challenge for physicians.

    Authors: Caroline T. Nguyen, Elizabeth B. Sasso, Lorayne Barton and Jorge H. Mestman

    Citation: Clinical Diabetes and Endocrinology 2018 4:4

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  20. Content type: Research article

    Endocrine profiles have been measured on blood samples obtained immediately post-competition from 693 elite athletes from 15 Olympic Sports competing at National or International level; four were subsequently ...

    Authors: Peter H. Sönksen, Richard I. G. Holt, Walailuck Böhning, Nishan Guha, David A. Cowan, Christiaan Bartlett and Dankmar Böhning

    Citation: Clinical Diabetes and Endocrinology 2018 4:3

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  21. Content type: Case report

    Ectopic insulin-like growth factor (IGF)-2 production is a rare complication of an array of epithelial and mesenchymal tumors, and can clinically manifest as life-threatening hypoglycemia.

    Authors: Eric D. Buras, Emily Weatherup and Jennifer Wyckoff

    Citation: Clinical Diabetes and Endocrinology 2018 4:2

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  22. Content type: Research article

    Empirical research has revealed a positive relationship between type 2 diabetes mellitus and depression, but questions remain regarding timing of depression measurement, types of instruments used to measure de...

    Authors: Jaimie C. Hunter, Brenda M. DeVellis, Joanne M. Jordan, M. Sue Kirkman, Laura A. Linnan, Christine Rini and Edwin B. Fisher

    Citation: Clinical Diabetes and Endocrinology 2018 4:1

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  23. Content type: Research article

    Since few studies have characterized painful diabetic peripheral neuropathy (pDPN) symptoms in multicultural populations, this study fielded a survey to better understand pDPN and its impact in African-America...

    Authors: Martin Eichholz, Andrea H. Alexander, Joseph C. Cappelleri, Patrick Hlavacek, Bruce Parsons, Alesia Sadosky and Michael M. Tuchman

    Citation: Clinical Diabetes and Endocrinology 2017 3:12

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  24. Content type: Case report

    Primary care clinicians will see a higher incidence of type 2 diabetes in adult patients, and the diagnosis and management of an initial presentation of type 1 diabetes can pose challenges to clinicians who se...

    Authors: Cristen P. Page, Brian Fitzgerald and Emily M. Hawes

    Citation: Clinical Diabetes and Endocrinology 2017 3:11

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  25. Content type: Review article

    Diabetic Retinopathy (DR) is a leading cause of visual impairment in the United States. The CDC estimates that the prevalence of DR will triple from 2005 to 2050.

    Authors: Anjali R. Shah and Thomas W. Gardner

    Citation: Clinical Diabetes and Endocrinology 2017 3:9

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  26. Content type: Review article

    There are two genes that express the major thyroid hormone receptor isoforms. Mutations in both these genes have given rise to Resistance to Thyroid Hormone (RTH) syndromes (RTHβ, RTHα) that can have variable ...

    Authors: Brijesh K. Singh and Paul M. Yen

    Citation: Clinical Diabetes and Endocrinology 2017 3:8

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  27. Content type: Research article

    Almost 20 years ago, the frequencies of severe hypoglycemia requiring emergency medical treatment were reported in people with types 1 and 2 diabetes in the Tayside region of Scotland. With subsequent improvem...

    Authors: Huan Wang, Peter T. Donnan, Callum J. Leese, Edward Duncan, David Fitzpatrick, Brian M. Frier and Graham P. Leese

    Citation: Clinical Diabetes and Endocrinology 2017 3:7

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  28. Content type: Research article

    Pulmonary diseases are often complicated and have diverse etiologies. One common factor is the lack of therapeutics available for these diseases. The goal of this study was to investigate the impact of Renin-A...

    Authors: Maira Soto, Soo I. Bang, Jeff McCombs and Kathleen E. Rodgers

    Citation: Clinical Diabetes and Endocrinology 2017 3:6

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  29. Content type: Research article

    Rapid-acting insulin analogs (RAIs) have not been examined for long-term safety in randomized clinical trials. We performed a nationwide longitudinal cohort study among individuals with type 2 diabetes (T2DM) ...

    Authors: Ann-Marie Svensson, Mervete Miftaraj, Stefan Franzén and Björn Eliasson

    Citation: Clinical Diabetes and Endocrinology 2017 3:5

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  30. Content type: Review article

    Examine Peer Support (PS) for complex, sustained health behaviors in prevention or disease management with emphasis on diabetes prevention and management.

    Authors: Edwin B. Fisher, Renée I. Boothroyd, Emily A. Elstad, Laura Hays, Amy Henes, Gary R. Maslow and Clayton Velicer

    Citation: Clinical Diabetes and Endocrinology 2017 3:4

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  31. Content type: Research article

    It is estimated that 9.3% of the population in the United States have diabetes mellitus (DM), 28% of which are undiagnosed. The high prevalence of DM makes it a common comorbid condition in hospitalized patien...

    Authors: Stephanie Ostling, Jennifer Wyckoff, Scott L. Ciarkowski, Chih-Wen Pai, Hae Mi Choe, Vinita Bahl and Roma Gianchandani

    Citation: Clinical Diabetes and Endocrinology 2017 3:3

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  32. Content type: Research article

    Charcot neuroarthopathy (CN), a rare foot and ankle condition usually complicating diabetes mellitus, leads to deformity, poor quality of life, and increased mortality and morbidity. The prevalence of this con...

    Authors: Brian M. Schmidt, James S Wrobel and Crystal M. Holmes

    Citation: Clinical Diabetes and Endocrinology 2017 3:2

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  33. Content type: Research article

    Safe and effective diabetes management in the hospital is challenging. Inadequate knowledge has been identified by trainees as a key barrier. In this study we assess both the short-term and long-term impact of...

    Authors: Timothy W. Bodnar, Jennifer J. Iyengar, Preethi V. Patil and Roma Y. Gianchandani

    Citation: Clinical Diabetes and Endocrinology 2016 2:20

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  34. Content type: Review article

    Thyroid-associated ophthalmopathy (TAO) is a condition associated with a wide spectrum of ocular changes, usually in the context of the autoimmune syndrome, Graves’ disease. In this topical review, we attempte...

    Authors: Priscila Novaes, Ana Beatriz Diniz Grisolia and Terry J. Smith

    Citation: Clinical Diabetes and Endocrinology 2016 2:19

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  35. Content type: Review article

    The prevalence of diabetes in children and adolescents is increasing worldwide, with profound implications on the long-term health of individuals, societies, and nations. The diagnosis and management of diabet...

    Authors: Ranjit Unnikrishnan, Viral N. Shah and Viswanathan Mohan

    Citation: Clinical Diabetes and Endocrinology 2016 2:18

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  36. Content type: Review article

    Thyroid nodules are common. The clinical importance of thyroid nodules is related to excluding malignancy (4.0 to 6.5% of all thyroid nodules), evaluate their functional status and assess for the presence of p...

    Authors: Shrikant Tamhane and Hossein Gharib

    Citation: Clinical Diabetes and Endocrinology 2016 2:17

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  37. Content type: Review article

    Cushing’s disease (CD) is the most common cause of endogenous Cushing’s syndrome (CS). The goal of treatment is to rapidly control cortisol excess and achieve long-term remission, to reverse the clinical featu...

    Authors: Daniel Cuevas-Ramos, Dawn Shao Ting Lim and Maria Fleseriu

    Citation: Clinical Diabetes and Endocrinology 2016 2:16

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  38. Content type: Review article

    Hypophysitis is the acute or chronic inflammation of the pituitary gland. The spectrum of hypophysitis has expanded in recent years with the addition of two histologic subtypes and recognition as a complicatio...

    Authors: Alexander Faje

    Citation: Clinical Diabetes and Endocrinology 2016 2:15

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  39. Content type: Review article

    Pancreas transplantation (PTX) has been demonstrated to restore long-term glucose homeostasis beyond what can be achieved by intensive insulin therapy or islet transplants. Moreover, PTX has been shown to decr...

    Authors: Marcio W Lauria and Antonio Ribeiro-Oliveira Jr

    Citation: Clinical Diabetes and Endocrinology 2016 2:14

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  40. Content type: Review article

    Gestational diabetes mellitus (GDM) is one of the most common metabolic complications of pregnancy. Ever since the first systematic evaluation of the oral glucose tolerance test by O’Sullivan and colleagues wa...

    Authors: B. Bhavadharini, R. Uma, P. Saravanan and V. Mohan

    Citation: Clinical Diabetes and Endocrinology 2016 2:13

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  41. Content type: Research article

    This report evaluated the cardiovascular safety of the amylin analog pramlintide—an existing diabetes injectable treatment—by comparing relevant cardiovascular adverse events (AEs) reported in previous phase 3...

    Authors: Kathrin Herrmann, Ming Zhou, Andrew Wang and Tjerk W. A. de Bruin

    Citation: Clinical Diabetes and Endocrinology 2016 2:12

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  42. Content type: Research article

    Intra-islet insulin contributes to alpha-cell suppression. Akita mice carry a toxic-gain-of- function Ins2 gene mutation encoding proinsulin-C(A7)Y, similar to that described in human Mutant Ins-gene induced Diab...

    Authors: Fabrizio Barbetti, Carlo Colombo, Leena Haataja, Corentin Cras-Méneur, Sergio Bernardini and Peter Arvan

    Citation: Clinical Diabetes and Endocrinology 2016 2:11

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Clinical Diabetes and Endocrinology is published in collaboration with the University of Michigan.

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